jm's Adventure with Multiple Myeloma: 2nd Relapse Confirmed By Bone Marrow Biopsy Done 17 October 2012

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Monday, October 22, 2012

2nd Relapse Confirmed By Bone Marrow Biopsy Done 17 October 2012

I received part of my bone marrow biopsy results done on the sample obtained 17 October 2012 at the University of Colorado Hospital this afternoon. 

My bone marrow reveals relapsed plasma cell myeloma with 60 % kappa monotypic plasma cells involving a slightly hypercellular marrow (70 %) with mild anemia (low hemoglobin) and moderate thrombocytopenia (low platelets). I do not have the cytogenetic analyses yet.

So, this report is even worse than I thought it would be with an M-Spike measured at UCH on 17 October 2012 of only 0.3. Plus, it is clearly apparent that the 2nd autologous stem cell transplant did nothing for me.

I'll just have to wait for the referral to Boston and the approval of Carfilzomib and Revlimid. I go to see Dr. Padavanija at St. Luke's Hospital MSTI in Twin Falls, Idaho tomorrow. If they don't have the Carfilzomib approval, I'll get Velcade again.

Snowing in our mountains today.


  1. I'm sorry to hear that news. Hope you hear better news tomorrow.

  2. Here's hoping that you will be cleared for Carfilzomib tomorrow and that you will be able to leave for Boston soon. You are in our thoughts and prayers. Good luck tomorrow! Drive safe!
    Dianne and Clark

  3. Sorry to hear the news isn't great. Good luck tomorrow. Keep strong, Sharyn

  4. Although this numbers game is distressing, I want to let you know that an MM pal of mine was given his 'processing papers' and told by his doctor that his train was leaving the station in six months. He went home and sold or gave away all sorts of things and began the wait... when I happened on the scene he was the most terminal fellow in both attitude and energy I've ever talked to. But his 'day' arrived and he was still feeling like he should do something more...and he started really writing seriously both on his blog and elsewhere... he has bypassed what he refers to as his 'shelf date' by three years and is still going strong.

    So don't let the numbers start ruling your life just yet... and I am sure your readers will join me in the intention that you are getting some new and good solutions for the highest and best good of all concerned, so be it and so it is!

    PS - I used to love this time of year when I lived in Sun Valley (ID) and that first snow covered the golden leaves of the aspen.... sigh - so pretty!

  5. Thanks everyone for your concern and notes. I'm really not down and hopeful that the new line of drugs Carfilzomid will help me. jm

  6. I am so sorry that you are going through all of this. I am amazed at how you cope with all the ups and downs.

  7. Thanks Jane - I'm just going day to day and so far I feel pretty well. jm